DOLF Team receives a $1.8 million Bill and Melinda Gates Foundation Grant to Explore Lymphatic Filariasis Elimination in Indonesia

DOLF Team receives a $1.8 million Bill and Melinda Gates Foundation Grant to Explore Lymphatic Filariasis Elimination in Indonesia

Over a decade ago, Indonesia had one of the largest populations endemic for lymphatic filariasis (LF) in the world with 50% of the districts endemic for this mosquito borne disease. The country consists of 6,000 inhabited island and stretches over 3,000 miles from east to west. While some districts have eliminated LF by mass drug […]

DOLF Presentations – ASTMH Meeting

DOLF Presentations at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (Virtual, November 2021) Symposium: Clinical development of new treatments to support the global elimination of onchocerciasis. GJ Weil, C Hanson, N Opoku, A Hoerauf, S. Specht, M Sullivan. Coverage and impact of a single dose of ivermectin, DEC and albendazole […]

Highlighting DOLF Publications

First Half of 2021 Eneanya OA, Koudou BG, Aboulaye M, Elvis AA, Souleymane Y, Kouakou MM, Weil GJ, Fischer PU. Progress towards onchocerciasis elimination in Côte d’Ivoire: A geospatial modelling study. PLoS Negl Trop Dis. 2021 Feb 10;15(2):e0009091. doi:10.1371/journal.pntd.0009091. eCollection 2021 Feb PMID: 33566805. This study reviewed dramatic improvements in onchocerciasis endemicity that have occurred […]

Publications from Clinical Trials

The DOLF project is pleased to share several recent publications from clinical trials and community studies of alternative treatments for lymphatic filariasis. All of these have been published with open access. The first two articles (by Campillo et al and Ouattara et al) provide further strong evidence in support of the WHO recommendation to use […]

Eleven DOLF Project publications on triple drug (IDA) mass drug administration for elimination of lymphatic filariasis have now been bundled as a PLoS Collection

PloS “Collections” are useful for readers and researchers alike, because provide easy access to related articles on high priority topics that have been published in PLoS journals at different times. This collection (published June 16, 2022) focuses on clinical trials and community studies of the safety, efficacy, and acceptability of the triple drug regimen IDA […]
The DOLF Team’s Work to Improve Prospects for Elimination of LF Featured in a Special Supplement Published in the Am. J. Trop. Med. Hyg. (March 2022)

The DOLF Team’s Work to Improve Prospects for Elimination of LF Featured in a Special Supplement Published in the Am. J. Trop. Med. Hyg. (March 2022)

The DOLF project (www.dolfproject.wustl.edu) led clinical trials and community studies of the safety and efficacy of a single-dose triple-drug therapy (IDA) for Lymphatic Filariasis (LF). IDA is now being used in mass drug administration (MDA) programs in many countries to accelerate LF elimination. This work was supported by grants from the Bill & Melinda Gates […]

Development of new treatments for Riverblindness

Development of new treatments for Riverblindness: Facilitated histological assessment of Onchocerca volvulus nodules to detect treatment effects on adult worms Adult O. volvulus worms reside in subcutaneous nodules and can live up to 15 years. It requires special expert knowledge to differentiate natural morphological changes during its life span from changes induced by anti-filarial drugs […]
DOLF team to provide clinical care to men with hydrocele in Cote d’Ivoire

DOLF team to provide clinical care to men with hydrocele in Cote d’Ivoire

With support from the Bill and Melinda Gates Foundation, and in partnership with the local partner Swiss Center for Scientific research in Cote d’Ivoire and the Ivorian National NTD Program, DOLF investigators helped organizing surgical hydrocelectomy training this week in Agboville, Cote d’Ivoire.  Eight surgeons from various parts of Cote d’Ivoire, 2 nurses, and 2 […]

Welcome Betsy Abente, the DOLF Program’s new Global Health Program Manager for Administration and Finance

Joining the team in November, Betsy brings over 15 years of global health experience, including nearly a decade of research administration at Washington University to the team. In her previous role as Associate Director for the International Center for Child Health and Development, she helped develop and manage the center’s growing capacity building arm as […]
DOLF team recognized for their research on LF in Ivory Coast

DOLF team recognized for their research on LF in Ivory Coast

DOLF researchers Benjamin Koudou, Allassane Ouattara, Catherine Bjerum, and colleagues were recently honored to receive the 11th CSRS-Eremitage Fund Prize for Scientific Research in Partnership from the Swiss Center for Scientific Research in Côte d’Ivoire. The prize recognizes the team’s pioneering research on new treatments for lymphatic filariasis, a disabling and disfiguring parasitic disease that […]
Dr. Fatorma Bolay

Dr. Fatorma Bolay

Dr. Fatorma Bolay, the director of the Division of Public Health Research at the National Public Health Institute of Liberia (NPHIL) has passed away. He was the director of the former Liberian Institute for Biomedical Research (LIBR) and DOLF-Project collaborator since 2011. Dr. Bolay navigated the LIBR through difficult times in Liberia and was a […]
Onchocerciasis elimination in Côte d’Ivoire

Onchocerciasis elimination in Côte d’Ivoire

The DOLF Project has just published an article on the spatial distribution of onchocerciasis (Oncho) in Côte d’Ivoire before and after the introduction of mass distribution of ivermectin. This work was based on extensive Ministry of Health mapping and surveillance data collected between 1975 and 2016. Data included village geolocations, village-level prevalence and intensity estimates […]