The DOLF Project has Initiated a Clinical Trial of New Treatments for Onchocerciasis in Liberia
DOLF researchers announce initiation of a major a new clinical trial of treatments for onchocerciasis in Liberia. The study will compare the safety and efficacy of three new combination treatments with a reference treatment of albendazole plus ivermectin. DOLF researchers have worked closely for the past 18 months with colleagues at the National Public Health […]
DOLF Team’s 2023 in Review
Happy 2024 from the DOLF team! From the field to the lab and back again, here is a brief snap shot of our 2023, a year that saw many new advances and developments in our research on lymphatic filariasis (LF) and onchocerciasis (oncho). As an added bonus, we even learned the best bait for catching […]
A New DOLF Publication Highlights Promising New Results in Support of Onchocerciasis Elimination
Onchocerciasis (“river blindness”), a parasitic disease that leads to debilitating and stigmatizing ailments, has been targeted by the World Health Organization for elimination. New drug treatments that kill or permanently sterilize female worms could accelerate this process. The DOLF team, together with our partners at the University of Health and Allied Sciences (UHAS) in Ghana […]
Welcome to DOLF’s new Postdoctoral Research Associate- Dr. Adebiyi Adeniran
Adebiyi is a molecular entomologist and molecular parasitologist with over a decade of Neglected Tropical Disease (NTD) research and control program experience in sub-Saharan Africa and in Mexico. Adebiyi has previously worked as the Regional Technical Lead for NTD diagnostics for Sightsavers UK, where he provided technical and advisory support to NTD control programs in […]
DOLF Presentations – ASTMH Meeting
DOLF Presentations at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (Virtual, November 2021) Symposium: Clinical development of new treatments to support the global elimination of onchocerciasis. GJ Weil, C Hanson, N Opoku, A Hoerauf, S. Specht, M Sullivan. Coverage and impact of a single dose of ivermectin, DEC and albendazole […]
Highlighting DOLF Publications
First Half of 2021 Eneanya OA, Koudou BG, Aboulaye M, Elvis AA, Souleymane Y, Kouakou MM, Weil GJ, Fischer PU. Progress towards onchocerciasis elimination in Côte d’Ivoire: A geospatial modelling study. PLoS Negl Trop Dis. 2021 Feb 10;15(2):e0009091. doi:10.1371/journal.pntd.0009091. eCollection 2021 Feb PMID: 33566805. This study reviewed dramatic improvements in onchocerciasis endemicity that have occurred […]
Publications from Clinical Trials
The DOLF project is pleased to share several recent publications from clinical trials and community studies of alternative treatments for lymphatic filariasis. All of these have been published with open access. The first two articles (by Campillo et al and Ouattara et al) provide further strong evidence in support of the WHO recommendation to use […]
DOLF Welcomes New Research Administrator
The DOLF Project is excited to welcome Kassandra Huneycutt, our new Research Administrator. Kassandra brings three years of experience as a Post-Award Grant Specialist within the Office of Research at the University of Central Florida and six years of experience as a Grants Specialist with Wycliffe Bible Translators. In her new role, Kassandra will be […]
DOLF Welcomes New Associate Director
In July, the DOLF Project welcomed Laura Peer in the new role of Associate Director Global Health Research. In her new role with the DOLF Project, Laura will oversee office administration and field operations, as well as support strategic planning and center communications. Laura most recently worked for the International Center for Child Health and […]
The DOLF Project Welcomed Public Health Summer Research Program Student, Michael Poirier
The DOLF Project hosted Gold Family Summer Research Scholar Michael Poirier this summer through the 2024 Institute for Public Health Summer Research Program. Michael is a rising senior at Saint Louis University studying Public Health and Psychology. He had a productive summer, completing several important projects with the DOLF Project, a research center and lab […]
DOLF Initiating a Follow Up Study on Moxidectin plus Albendazole (MoxA) Combination Treatment for Lymphatic Filariasis and Onchocerciasis in Cote d’Ivoire
DOLF investigators are beginning a follow-up study on the efficacy of a new combination treatment for lymphatic filariasis (LF) and onchocerciasis in the Akoupé district of Côte d’Ivoire. This study began July 4th and builds upon a large-scale community survey sponsored by Medicines Development for Global Health (MDGH). This study aims to determine whether moxidectin […]
Gary J. Weil Installed as the Inaugural Gerald and Judith Medoff Professor of Infectious Diseases
Gary J. Weil, MD, co-principal investigator of the DOLF Project, was installed as the inaugural Gerald and Judith Medoff Professor of Infectious Diseases on January 29, 2024 at Washington University in St. Louis.
DOLF Co-Founder and Co-Director Dr. Gary Weil receives the prestigious Kyelem Prize
We are pleased to share the news that DOLF Co-Director, Gary Weil received the 2023 Kyelem Prize at the annual Coalition for Operational Research on Neglected Tropical Diseases (COR-NTD). Described by some as the “Oscar” of neglected tropical disease (NTD) research, this prize recognizes people in the field who have been particularly effective in bringing […]
The Role of Monkeys as a Reservoir for the Lymphatic Filarial Parasite Brugia malayi on Belitung Island, Indonesia
In May 2023 Irina Diekmann, a veterinarian and postdoc at Washington University, traveled to Belitung Island, Indonesia to assist Professor Taniawati Supali and her team at the Universitas Indonesia, trap crab-eating macaques for blood collection to determine if they are a potential animal reservoir of B. malayi. B. malayi, a filarial nematode and one of […]
DOLF Team Supports New Clinical Trial in Cote d’Ivoire
The DOLF Team Supports a New Clinical Trial in Côte d’Ivoire to Test Safety of Moxidectin in Regions co-Endemic to Onchocerciasis and Lymphatic Filiariasis Onchocerciasis (oncho), also known as river blindness, is a serious, debilitating, and stigmatizing parasitic disease. It is a major neglected tropical disease that causes severe skin disease and blindness in more […]
The DOLF Team’s 2022: Year in Review
As we look towards a new year, we wanted to share some highlights from 2022, a year that saw many new advances and developments in our research on Lymphatic Filariasis (LF) and Onchocerciasis (Oncho). LF research Cote d’Ivoire. In late winter, DOLF team members traveled to Côte d’Ivoire for 12-month follow-up visits for patients enrolled […]