Study
Safety and efficacy of IDA as a mass drug administration regimen for elimination of lymphatic filariasis
Study Site: Yadgir district, Karnataka
This study compared the safety and efficacy of mass drug administration (MDA) with triple drug regimen of ivermectin, diethylcarbamazine, and albendazole “IDA” with the standard MDA treatment regimen of diethylcarbamazine (DEC) and albendazole “DA”. The results showed that IDA and DA had comparable safety profiles and that both regimens were acceptable to the population. Follow-up studies showed that IDA was superior to DA for clearing microfilaremia, an important indicator of infection.
Implementation Partners
Research Collaborator
Dr. P. Jambulingam, Director, ICMR-VCRC, Puducherry, India
Coordinating Investigators
Washington University School of Medicine, St. Louis, Missouri
Dr. Gary Weil and Dr. Ramakrishna Rao